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Dermatomyositis induced by the secretion of Phyllomedusa bicolor or Kambô frog - A case report.
Toxicon ( IF 2.6 ) Pub Date : 2020-05-28 , DOI: 10.1016/j.toxicon.2020.05.018
Mariana de la Vega 1 , Gilberto Maldonado 2 , Arnoldo Kraus 3
Affiliation  

The Amazonian Kambô frog, Phyllomedusa bicolor, is commonly known for the potential benefits of its secretion. The Kambô ritual consists in applying the toxin directly to a freshly burnt skin area, since it is believed by natives and shamans to purify and strengthen the body and mind of the user. We describe a 33-year old female with a history of periodic use of Kambô toxin who presented with a 3-week course of asthenia, malaise, myalgia, and proximal muscle weakness predominantly in the lower limbs. She had elevated muscle enzymes and an abnormal electromyography. We used the 2017 European League Against Rheumatism and American College of Rheumatology classification criteria to establish the diagnosis of dermatomyositis. The patient demonstrated clinical response to prednisone, with a complete recovery of signs and symptoms after 8 weeks of treatment. To our knowledge, this is the first case report of dermatomyositis possibly associated with the use of Kambô. The Kambô cleansing ritual is becoming popular in first world countries, but its use may lead to serious side-effects, sometimes life-threatening. In patients presenting with signs and symptoms suggestive of dermatomyositis and a skin line of circle-shaped burns, Phyllomedusa bicolor skin secretion exposure should be suspected.



中文翻译:

双色毛状夜蛾或Kambô青蛙的分泌物引起的皮肌炎-病例报告。

亚马孙Kambô青蛙,双色Phyllomedusa 因其潜在的好处而广为人知。Kambô仪式是将毒素直接应用于刚烧过的皮肤区域,因为本地人和萨满教徒都认为该毒素可以净化和增强使用者的身心。我们描述了一位33岁的女性,她有定期使用Kambô毒素的病史,主要表现为下肢无力,乏力,肌痛和近端肌无力3周,共3周。她的肌肉酶升高,肌电图异常。我们使用2017年欧洲抗风湿病联盟和美国风湿病学院分类标准来确定皮肌炎的诊断。该患者表现出对泼尼松的临床反应,治疗8周后体征和症状完全恢复。据我们所知,这是可能与使用Kambô有关的皮肌炎的首例病例报告。Kambô清洁仪式在第一世界国家变得越来越流行,但是使用它可能会导致严重的副作用,有时甚至危及生命。如果患者的症状和体征提示皮肌炎和皮肤烧伤,应怀疑楠(Phyllomedusa)皮肤分泌物暴露。

更新日期:2020-05-28
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