Objective

The purpose of this narrative review is to summarize what is currently known about the structural, chemical, and mechanical properties of cartilage-bone interfaces, which provide tissue integrity across a bimaterial interface of 2 very different structural materials. Maintaining these mechanical interfaces is a key factor for normal bone growth and articular cartilage function and maintenance.

Materials and Methods

A comprehensive search was conducted using Google Scholar and PubMed/Medline with a specific focus on the growth plate cartilage–subchondral bone interface. All original articles, reviews in journals, and book chapters were considered. Following a review of the overall structural and functional characteristics of the physis, the literature on histological studies of both articular and growth plate chondro-osseous junctions is briefly reviewed. Next the literature on biochemical properties of these interfaces is reviewed, specifically the literature on elemental analyses across the cartilage–subchondral bone junctions. The literature on biomechanical studies of these junctions at the articular and physeal interfaces is also reviewed and compared.

Results

Unlike the interface between articular cartilage and bone, growth plate cartilage has 2 chondro-osseous junctions. The reserve zone of the mature growth plate is intimately connected to a plate of subchondral bone on the epiphyseal side. This interface resembles that between the subchondral bone and articular cartilage, although much less is known about its makeup and formation.

Conclusion

There is a notably paucity of information available on the structural and mechanical properties of reserve zone–subchondral epiphyseal bone interface. This review reveals that further studies are needed on the microstructural and mechanical properties of chondro-osseous junction with the reserve zone.

中文翻译：

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软骨-软骨下骨连接的特性：特别关注生长板的叙述性评论。

客观的

这篇叙述性综述的目的是总结目前已知的关于软骨-骨界面的结构、化学和机械特性的知识，这些特性在两种截然不同的结构材料的双材料界面上提供了组织完整性。维持这些机械界面是正常骨骼生长和关节软骨功能和维持的关键因素。

材料和方法

使用 Google Scholar 和 PubMed/Medline 进行了全面搜索，特别关注生长板软骨-软骨下骨界面。所有原创文章、期刊评论和书籍章节都被考虑在内。在回顾了骨骺的整体结构和功能特征之后，简要回顾了有关关节和生长板软骨-骨连接处组织学研究的文献。接下来回顾了关于这些界面的生化特性的文献，特别是关于软骨-软骨下骨连接处元素分析的文献。还回顾和比较了关于关节和骺界面处这些连接处的生物力学研究的文献。

结果

与关节软骨和骨之间的界面不同，生长板软骨有 2 个软骨-骨连接处。成熟生长板的保留区与骨骺侧的软骨下骨板紧密相连。这个界面类似于软骨下骨和关节软骨之间的界面，尽管对其构成和形成知之甚少。

结论

关于储备区 - 软骨下骨骺骨界面的结构和机械特性的信息明显缺乏。本综述表明，需要进一步研究软骨-骨结合部与储备区的微观结构和力学性能。