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Syndecan-4 forces integrins to cooperate.
Nature Materials ( IF 37.2 ) Pub Date : 2020-05-27 , DOI: 10.1038/s41563-020-0689-5
Christophe Guilluy 1 , Monika E Dolega 1
Affiliation  

While integrin-based adhesions are thought to underlie many aspects of cell response to localized tension, another matrix receptor, syndecan-4, has now been shown to act as a mechanosensor, which triggers cell-wide integrin activation and adhesion reinforcement.

中文翻译:

Syndecan-4迫使整合素进行合作。

虽然基于整联蛋白的粘附被认为是细胞对局部张力反应的许多方面的基础,但现已证明另一种基质受体syndecan-4可以作为机械传感器,触发整个细胞的整联蛋白活化和粘附增强。
更新日期:2020-05-27
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