Taenia solium neurocysticercosis (NCC) is endemic in most of the world and contributes significantly to the burden of epilepsy and other neurological morbidity. Also present in developed countries because of immigration and travel, NCC is one of few diseases targeted for eradication. This paper reviews all aspects of its life cycle (taeniasis, porcine cysticercosis, human cysticercosis), with a focus on recent advances in its diagnosis, management, and control. Diagnosis of taeniasis is limited by poor availability of immunological or molecular assays. Diagnosis of NCC rests on neuroimaging findings, supported by serological assays. The treatment of NCC should be approached in the context of the particular type of infection (intra- or extraparenchymal; number, location, and stage of lesions) and has evolved toward combined symptomatic and antiparasitic management, with particular attention to modulating inflammation. Research on NCC and particularly the use of recently available genome data and animal models of infection should help to elucidate mechanisms of brain inflammation, damage, and epileptogenesis.

中文翻译：

---

猪带绦虫囊尾蚴病及其对神经系统疾病的影响。

猪带绦虫神经囊尾蚴病（NCC）在世界大部分地区流行，严重加重了癫痫和其他神经系统疾病的负担。由于移民和旅行，NCC 也出现在发达国家，它是为数不多的需要根除的疾病之一。本文综述了其生命周期的各个方面（绦虫病、猪囊尾蚴病、人囊尾蚴病），重点介绍了其诊断、管理和控制的最新进展。由于免疫学或分子检测的可用性较差，绦虫病的诊断受到限制。NCC 的诊断依赖于神经影像学检查结果，并得到血清学检测的支持。NCC 的治疗应根据特定类型的感染（实质内或外；病变的数量、位置和阶段）进行治疗，并已发展为对症治疗和抗寄生虫治疗相结合，特别注意调节炎症。对 NCC 的研究，特别是使用最近获得的基因组数据和感染动物模型，应有助于阐明脑部炎症、损伤和癫痫发生的机制。