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Phytochemical Profiles and Antioxidant Activity of Rehmannia glutinosa from Different Production Locations
Chemistry & Biodiversity ( IF 2.9 ) Pub Date : 2020-07-10 , DOI: 10.1002/cbdv.202000341
Wei Liu 1 , Dong-Xue Yin 2 , Tong Zhang 1 , Qi Qiao 1 , Yue-Qin Yang 1 , Wen-Lu Wang 1
Affiliation  

The chemical components and antioxidant activity of 16 Rehmannia glutinosa samples were investigated to reveal the high-quality raw resource for pharmaceutical products. 22 main chemical components were detected, with significant content differences ( P <0.05). 14 substances contents reached the maximum in S1 sample, such as catalpol (6.74 mg g -1 ), rehmaionoside A (1.93 mg g -1 ) and rehmannioside D (5.13 mg g -1 ). However, the content distribution of the other 8 substances had no obvious change regulation. Three antioxidant evaluation methods commonly showed S1 sample had strong antioxidant activity, with low IC 50 value of 0.022 mg mL -1 , high ABTS value of 524.196 μmol equiv. Trolox g -1 , and high FRAP value of 200.517 μmol equiv. Trolox g -1 . Considered the medicinal value, S1 had high quality based on the present phytochemical profiles and antioxidant activity. These results also indicated root extracts of R. glutinosa could become useful supplement for pharmaceutical products as new antioxidant agents.

中文翻译:

不同产地地黄的植物化学特征和抗氧化活性

对16份熟地黄样品的化学成分和抗氧化活性进行了研究,以揭示优质的医药产品原料资源。检出22种主要化学成分,含量差异显着( P <0.05)。S1样品中有14种物质含量达到最大值,如梓醇(6.74 mg g -1 )、地黄皂苷A(1.93 mg g -1 )和地黄苷D(5.13 mg g -1 )。而其他8种物质的含量分布无明显变化规律。三种抗氧化性评价方法普遍表明,S1样品具有较强的抗氧化活性,IC 50 值为0.022 mg mL -1 ,ABTS值为524.196 μmol equiv。Trolox g -1 和 200.517 μmol 当量的高 FRAP 值。特洛克斯克 -1 。考虑到药用价值,基于目前的植物化学特征和抗氧化活性,S1 具有高质量。这些结果还表明,R. glutinosa 的根提取物可以作为新的抗氧化剂成为医药产品的有用补充剂。
更新日期:2020-07-10
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