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The immunoregulatory function of polyphenols: implications in cancer immunity.
The Journal of Nutritional Biochemistry ( IF 5.6 ) Pub Date : 2020-05-26 , DOI: 10.1016/j.jnutbio.2020.108428
José Tarcísio Giffoni de Carvalho 1 , Debora Da Silva Baldivia 1 , David Tsuyoshi Hiramatsu de Castro 1 , Helder Freitas Dos Santos 1 , Cintia Miranda Dos Santos 1 , Alex Santos Oliveira 1 , Tamaeh Monteiro Alfredo 1 , Kellen Natalice Vilharva 1 , Kely de Picoli Souza 1 , Edson Lucas Dos Santos 1
Affiliation  

Polyphenols have demonstrated several potential biological activities, notably antitumoral activity dependent on immune function. In the present review, we describe studies that investigated antitumor immune responses influenced by polyphenols and the mechanisms by which polyphenols improve the immune response. We also discuss the limitations in related areas, especially unexplored areas of research, and next steps required to develop a therapeutic approach utilizing polyphenols in oncology.



中文翻译:

多酚的免疫调节功能:对癌症免疫力的影响。

多酚已显示出几种潜在的生物学活性,特别是依赖于免疫功能的抗肿瘤活性。在本综述中,我们描述了研究受多酚影响的抗肿瘤免疫应答以及多酚改善免疫应答机制的研究。我们还将讨论相关领域的局限性,尤其是未探索的研究领域,以及在肿瘤学中开发利用多酚的治疗方法所需的下一步。

更新日期:2020-05-26
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