Several species of eukaryotic organisms living in the high mountain areas of Armenia with naturally occurring levels of radiation have high adaptive responses to radiation. We speculate on the role of the gastrointestinal microbiota in this protection against radiation. Therefore, seventeen microorganisms with high antagonistic activities against several multi-drug-resistant pathogens were isolated from the human and animal gut microbiota, as well as from traditional Armenian fermented products. These strains were tested in vivo on Wistar rats to determine their ability to protect the eukaryotic host against radiation damages. The efficiency of the probiotics’ application and the dependence on pre- and post-radiation nutrition of rats were described. The effects of Lactobacillus rhamnosus Vahe, isolated from a healthy breastfed infant, and Lactobacillus delbrueckii IAHAHI, isolated from the fermented dairy product matsuni, on the survival of irradiated rats, and their blood leucocyte and glucose levels, were considered to be the most promising, based on this study’s results.

生活在亚美尼亚高山地区的几种真核生物具有自然发生的辐射水平，对辐射具有很高的适应性。我们推测胃肠道菌群在这种辐射防护中的作用。因此，从人和动物肠道菌群以及传统的亚美尼亚发酵产物中分离出了对几种耐多药病原体具有高拮抗活性的十七种微生物。这些菌株在Wistar大鼠体内进行了测试，以确定它们保护真核宿主免受辐射损害的能力。描述了益生菌施用的效率以及对大鼠辐射前和辐射后营养的依赖性。鼠李糖乳杆菌的作用根据这项研究的结果，从健康的母乳喂养婴儿中分离出的Vahe和从发酵乳制品matsuni中分离出的德氏乳杆菌IAHAHI，对受辐照的大鼠的存活以及其白血球和血糖水平被认为是最有前途的。