Purpose

Equine piroplasmosis is a tick-borne protozoal disease affecting horses, mules, donkeys and zebras and can lead to severe economic losses in the equine industry. There is limited information on clinical pathologic changes of equine piroplasmosis in donkeys. This study aims to investigate the impacts of babesiosis on various hematological and biochemical properties in naturally infected donkeys with Theileria equi and Babesia caballi.

Methods

A total of 200 apparently healthy donkeys were randomly examined for the presence of equine piroplasmosis in blood samples. Of 200 samples, 11(5.5%) animals were positive for T. equi and 3(1.5%) of the samples were infected with B. caballi. 14 uninfected donkeys, were also selected as a control group.

Results

The results of the comparison showed that infected donkeys presented a significant elevation (P < 0.05) of total leukocyte count, number of lymphocyte, monocyte, neutrophil and eosinophil, while showed a significant decreased in (P < 0.05) hemoglobin concentration (Hb), packed cell volume (PCV), red blood cells (RBCs), mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC). The infected donkeys had significantly higher levels of total protein and total bilirubin (P < 0.05), whereas the amount of albumin was significantly lower in comparison to healthy animals (P < 0.05). It is interesting to note that the amounts of urea, cholesterol, creatinine, triglyceride, LDL and HDL, CK, AST, LDH, GGT, and Malondialdehyde were significantly higher (P < 0.05) in infected donkeys.

Conclusions

The current study describes laboratory findings in the affected donkeys which were good criteria for diagnosis and control of equine piroplasmosis in donkeys.

中文翻译：

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伊朗西北部驴（Equus asinus）自然发生的马梨浆虫病的血液学和生化变化。

目的

马梨形虫病是一种蜱传播的原生动物疾病，影响马、骡、驴和斑马，并可能导致马业的严重经济损失。关于驴中马梨形虫病的临床病理变化的信息有限。本研究旨在调查巴贝斯虫病的各种血液和生化特性与自然感染驴的影响，泰勒球菌和驽巴贝虫。

方法

总共随机检查了 200 头明显健康的驴，以确定血液样本中是否存在马梨形虫病。200个样品中，11（5.5％）的动物呈阳性T.球菌样品被感染的和3（1.5％）B.巴贝斯。14头未感染的驴也被选为对照组。

结果

比较的结果表明，感染驴呈现的显著抬高（P 总白细胞计数<0.05），淋巴细胞，单核细胞，嗜中性粒细胞和嗜酸性粒细胞的数量，同时显示在（一个显著降低P  <0.05）血红蛋白浓度（血红蛋白），压实细胞体积 (PCV)、红细胞 (RBC)、平均红细胞体积 (MCV) 和平均红细胞血红蛋白浓度 (MCHC)。受感染的驴有显著更高水平的总蛋白和总胆红素（的P  <0.05），而白蛋白的量相比于健康动物中显著降低（P < 0.05)。有趣的是，尿素、胆固醇、肌酐、甘油三酯、低密度脂蛋白和高密度脂蛋白、CK、AST、LDH、GGT 和丙二醛的含量 在感染驴中显着升高（P < 0.05）。

结论

目前的研究描述了受影响驴的实验室发现，这些发现是诊断和控制驴中马梨浆虫病的良好标准。