Asymmetric N-alkylation of indoles with isatins catalyzed by N-heterocyclic carbene: efficient synthesis of functionalized cyclic N,O-aminal indole derivatives,Organic Chemistry Frontiers

当前位置： X-MOL 学术 › Org. Chem. Front. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Asymmetric N-alkylation of indoles with isatins catalyzed by N-heterocyclic carbene: efficient synthesis of functionalized cyclic N,O-aminal indole derivatives
Organic Chemistry Frontiers ( IF 5.4 ) Pub Date : 2020-05-26 , DOI: 10.1039/d0qo00237b
Chengyuan Wang _{1,

2,

3,

4,

5} , Zhuopeng Li _{1,

2,

3,

4,

5} , Jiong Zhang _{1,

2,

3,

4,

5} , Xin-Ping Hui _{1,

2,

3,

4,

5}

Affiliation

An N-heterocyclic carbene-catalyzed enantioselective N-alkylation of indole-2-formaldehydes with isatins has been achieved. Functionalized cyclic N,O-aminal indole derivatives were obtained in good yields with excellent enantioselectivities.

中文翻译：