Patients with novel coronavirus disease 2019 (COVID-19) experience various degrees of liver function abnormalities. Liver injury requires extensive work-up and continuous surveillance and can be multifactorial and heterogeneous in nature. In the context of COVID-19, clinicians will have to determine whether liver injury is related to an underlying liver disease, drugs used for the treatment of COVID-19, direct effect of the virus, or a complicated disease course. Recent studies proposed several theories on potential mechanisms of liver injury in these patients. This review summarizes current evidence related to hepatobiliary complications in COVID-19, provides an overview of the available case series and critically elucidates the proposed mechanisms and provides recommendations for clinicians.

2019新型冠状病毒病（COVID-19）患者会出现不同程度的肝功能异常。肝损伤需要广泛的检查和持续监测，并且本质上可能是多因素和异质性的。在 COVID-19 的背景下，临床医生必须确定肝损伤是否与潜在的肝脏疾病、用于治疗 COVID-19 的药物、病毒的直接影响或复杂的病程有关。最近的研究提出了一些关于这些患者肝损伤潜在机制的理论。本综述总结了与 COVID-19 肝胆并发症相关的当前证据，概述了现有病例系列，批判性地阐明了拟议的机制，并为临床医生提供了建议。