With a growing and aging population, cancer is and will remain a continuous health challenge. In particular, upper gastrointestinal cancers take a substantial share in the global cancer burden.¹ Although 5-year survival rates of various cancer types have improved, gastroesophageal cancer has remained low on the list.²,³ As signs of malignant obstruction mostly manifest when the tumour has invaded locoregional or even distant structures, many patients with gastroesophageal cancer present at an advanced stage, resulting in poor survival in this group.⁴

中文翻译：

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缩短胃食管癌的诊断时间是进一步改善预后的关键。

随着人口的增长和老龄化，癌症现在和将来仍然是一个持续的健康挑战。特别是，上消化道癌症在全球癌症负担中占有很大份额。¹尽管各种癌症类型的 5 年生存率有所提高，但胃食管癌的排名仍然较低。² , ³由于恶性梗阻的征象多在肿瘤侵犯局部甚至远处结构时表现出来，因此许多胃食管癌患者就诊时已是晚期，导致该组患者的生存率较差。⁴