当前位置: X-MOL 学术Prenat. Diagn. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
SARS-CoV-2 in the context of past coronaviruses epidemics: Consideration for prenatal care.
Prenatal Diagnosis ( IF 3 ) Pub Date : 2020-05-26 , DOI: 10.1002/pd.5759
Valentine Lambelet 1 , Manon Vouga 1 , Léo Pomar 1 , Guillaume Favre 1 , Eva Gerbier 1, 2, 3 , Alice Panchaud 2, 3, 4 , David Baud 1
Affiliation  

Since December 2019, the novel SARS‐CoV‐2 outbreak has resulted in millions of cases and more than 200 000 deaths worldwide. The clinical course among nonpregnant women has been described, but data about potential risks for women and their fetus remain scarce. The SARS and MERS epidemics were responsible for miscarriages, adverse fetal and neonatal outcomes, and maternal deaths. For COVID‐19 infection, only nine cases of maternal death have been reported as of 22 April 2020, and pregnant women seem to develop the same clinical presentation as the general population. However, severe maternal cases, as well as prematurity, fetal distress, and stillbirth among newborns have been reported. The SARS‐CoV‐2 pandemic greatly impacts prenatal management and surveillance and raise the need for clear unanimous guidelines. In this narrative review, we describe the current knowledge about coronaviruses (SARS, MERS, and SARS‐CoV‐2) risks and consequences on pregnancies, and we summarize available current candidate therapeutic options for pregnant women. Finally, we compare current guidance proposed by The Royal College of Obstetricians and Gynaecologists, The American College of Obstetricians and Gynecologists, and the World Health Organization to give an overview of prenatal management which should be utilized until future data appear.

中文翻译:

过去冠状病毒流行背景下的 SARS-CoV-2:产前护理的考虑。

自 2019 年 12 月以来,新型 SARS-CoV-2 疫情已在全球范围内造成数百万病例和超过 20 万人死亡。已经描述了非孕妇的临床病程,但有关女性及其胎儿潜在风险的数据仍然很少。SARS 和 MERS 流行病导致流产、胎儿和新生儿不良结局以及孕产妇死亡。对于 COVID-19 感染,截至 2020 年 4 月 22 日,仅报告了 9 例孕产妇死亡病例,孕妇似乎出现与普通人群相同的临床表现。然而,已有严重孕产妇病例以及新生儿早产、胎儿窘迫和死产的报道。SARS-CoV-2 大流行极大地影响了产前管理和监测,并提出了制定明确一致指南的必要性。在这篇叙述性综述中,我们描述了当前关于冠状病毒(SARS、MERS 和 SARS-CoV-2)风险和对妊娠的影响的知识,并总结了当前针对孕妇的候选治疗方案。最后,我们比较了英国皇家妇产科医师学会、美国妇产科医师学会和世界卫生组织提出的当前指南,以概述产前管理,在未来数据出现之前应予以利用。
更新日期:2020-05-26
down
wechat
bug