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Feline chimerism revealed by DNA profiling.
Animal Genetics ( IF 2.4 ) Pub Date : 2020-05-26 , DOI: 10.1111/age.12957
Ambre Jaraud 1 , Philippe Bossé 1 , Caroline Dufaure de Citres 2 , Laurent Tiret 1 , Vincent Gache 3 , Marie Abitbol 3, 4
Affiliation  

In dogs and cats, unusual coat colour phenotypes may result from various phenomena, including chimerism. In the domestic cat, the tortoiseshell coat colour that combines red and non‐red hairs is the most obvious way to identify chimeras in males. Several cases of tortoiseshell males have been reported, some of which were diagnosed as chimeras without any molecular confirmation. Here, we report the case of a female feline chimera identified thanks to its coat colour and confirmed through DNA profiling and a coat colour test. We ruled out the hypothesis of mosaicism and aneuploidy. All the data were consistent with a natural case of female chimerism.

中文翻译:

通过DNA分析揭示猫嵌合体。

在狗和猫中,不常见的毛色表型可能是由多种现象引起的,包括嵌合现象。在家猫中,将红色和红色头发结合在一起的the色是识别雄性嵌合体的最明显方法。据报道有几例of鱼男性,其中一些未经分子鉴定就被诊断为嵌合体。在这里,我们报告了由于其毛色而鉴定出的雌性猫嵌合体的病例,并通过DNA分析和毛色测试进行了确认。我们排除了镶嵌和非整倍性的假设。所有数据与女性嵌合体的自然情况一致。
更新日期:2020-07-01
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