Staphylococcus argenteus, characterized by the formation of non-pigmented (white) colonies, was recently identified as a new lineage separated from Staphylococcus aureus. However, correct identification of this lineage is difficult because of the similar characteristics to S. aureus. Here, we describe the first known case of keratoconjunctivitis due to S. argenteus in a 64-year-old man with diabetes. The symptoms of the patient were not improved by antibiotic therapy using levofloxacin eye drops (15 mg/mL). The conjunctival scraping was cultured, and coagulase-positive staphylococci forming white colonies were detected. Matrix-assisted laser desorption/ionization-time of flight mass spectrometry confirmed the species as S. argenteus with a spectral score of 1.97. After the antibiotic was changed to vancomycin eye drops (10 mg/mL), the patient's symptom clearly improved. Multi-locus sequence typing showed that this isolate belonged to sequence type 1223, which has been predominantly isolated worldwide. Furthermore, this isolate harbored various virulence genes associated with S. aureus, such as staphylococcal enterotoxins and leukocidin. Since only limited information is available for this organism, further studies are needed to establish the epidemiology of S. argenteus.

葡萄球菌argenteus，其特征在于通过非着色（白色）的菌落形成，最近被确定为一个新的谱系从分离的金黄色葡萄球菌。但是，由于与金黄色葡萄球菌相似的特征，因此很难正确鉴定该谱系。在这里，我们描述了在64岁的糖尿病患者中由阿根廷链球菌引起的第一个已知的角膜结膜炎病例。使用左氧氟沙星滴眼液（15 mg / mL）进行抗生素治疗不能改善患者的症状。培养结膜刮取物，并检测到形成凝固酶阳性葡萄球菌的白色菌落。基质辅助激光解吸/电离飞行时间质谱法确认该物种为阿根廷银链霉菌光谱得分为1.97。将抗生素改为万古霉素滴眼液（10 mg / mL）后，患者的症状明显改善。多基因座序列分型显示该分离株属于序列类型1223，该序列类型主要在世界范围内分离。此外，该分离物还具有与金黄色葡萄球菌相关的各种毒力基因，例如葡萄球菌肠毒素和白细胞介素。由于该生物的可用信息有限，因此需要进一步的研究来确定阿根廷链球菌的流行病学。