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Compressive myelopathy secondary to posthemorragic arachnoiditis: case report and literature review
Clinical Neurology and Neurosurgery ( IF 1.9 ) Pub Date : 2020-09-01 , DOI: 10.1016/j.clineuro.2020.105964
María López Gutiérrez 1 , Eduardo Enrique Espinosa Rodríguez 2 , Juan Martínez San Millán 3 , Luis Ley Urzaiz 1 , Víctor Rodríguez Berrocal 1
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BACKGROUND Spinal arachnoiditis is an arachnoid inflammatory process frequently caused by infection or spinal surgery; there are different degrees of severity, including arachnoid thickening and severe adhesive lesions that can lead to the development of arachnoid cysts. Non-traumatic subarachnoid haemorrhage (ntSAH) is a relatively uncommon cause of arachnoiditis; further complication with spinal cord compression (SCC) is even more unusual. METHOD we describe a 70-year-old female, with SCC caused by arachnoid cysts. Her medical past history was relevant for an episode of ntSAH after rupture of a posterior communicating artery aneurysm, eight months prior to the onset of symptoms. We also present a literature review of previous published cases. RESULTS we selected 23 articles with 24 case reports. A noticeable female predominance (11:1) was observed. It is more common between the fourth and fifth decades. The majority of cases (58 %) were secondary to aneurysmal SAH due to rupture of a posterior circulation aneurysm. The most common location of the cyst is in the cervicothoracic spine. The average time between the initial bleeding and symptom development is 3-6 months. The most frequently described treatment is laminectomy and marsupialization of the cyst, but reports show a high recurrence rate. CONCLUSIONS ntSAH is an uncommon aetiology of arachnoiditis and arachnoid cysts. SCC from arachnoid cysts secondary to ntSAH is exceptional. Treatment through laminectomy has a relatively high recurrence rate (33 %). We present different hypotheses to try to explain how the alteration of cerebrospinal fluid (CSF) dynamics after ntSAH can lead to arachnoid cyst development and SCC. Although the small number of cases included in the present series precludes us to draw definite conclusions, ventriculoperitoneal shunt (VPS) placement can be considered as an alternative treatment in the management of known ntSAH patients that present recurrent symptomatic arachnoid cysts.

中文翻译:

继发于出血后蛛网膜炎的压迫性脊髓病:病例报告和文献复习

背景脊髓蛛网膜炎是一种经常由感染或脊柱手术引起的蛛网膜炎症过程。有不同程度的严重程度,包括蛛网膜增厚和可导致蛛网膜囊肿发展的严重粘连性病变。非创伤性蛛网膜下腔出血 (ntSAH) 是一种相对少见的蛛网膜炎病因。脊髓压迫症 (SCC) 的进一步并发症更为罕见。方法 我们描述了一名 70 岁女性,患有由蛛网膜囊肿引起的 SCC。她的既往病史与症状出现前 8 个月后交通动脉瘤破裂后 ntSAH 发作有关。我们还对以前发表的案例进行了文献综述。结果 我们选择了 23 篇文章和 24 篇病例报告。明显的女性优势(11:1) 观察。在第四个和第五个十年之间更常见。由于后循环动脉瘤破裂,大多数病例 (58%) 继发于动脉瘤性 SAH。囊肿最常见的部位是颈胸椎。最初出血和症状发展之间的平均时间为 3-6 个月。最常描述的治疗方法是椎板切除术和囊肿的有袋动物化,但报告显示复发率很高。结论 ntSAH 是蛛网膜炎和蛛网膜囊肿的罕见病因。由继发于 ntSAH 的蛛网膜囊肿引起的 SCC 是例外。通过椎板切除术治疗的复发率相对较高(33%)。我们提出了不同的假设,试图解释 ntSAH 后脑脊液 (CSF) 动力学的改变如何导致蛛网膜囊肿发展和 SCC。
更新日期:2020-09-01
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