We introduce COVIDep (https://COVIDep.ust.hk), a web-based platform that provides immune target recommendations for guiding SARS-CoV-2 vaccine development. COVIDep implements a protocol that pools together publicly-available genetic data for SARS-CoV-2 and epitope data for SARS-CoV to identify B cell and T cell epitopes that present potential immune targets for SARS-CoV-2. Correspondences between outputs of COVIDep and immune responses recorded in COVID-19 patients and preclinical vaccine trials are also indicated. The platform is user-friendly, flexible, and based on up-to-date data. It may help guide vaccine designs and associated experimental studies for SARS-CoV-2.

中文翻译：

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用于SARS-CoV-2疫苗目标建议的实时报告的COVIDep平台：COVID-19免疫反应和临床前疫苗试验的描述和联系

我们介绍了基于网络的平台COVIDep（https://COVIDep.ust.hk），该平台可提供免疫目标建议以指导SARS-CoV-2疫苗的开发。COVIDep实现了一种协议，该协议将SARS-CoV-2的公共可用遗传数据与SARS-CoV的表位数据集中在一起，以识别呈现出SARS-CoV-2潜在免疫靶点的B细胞和T细胞表位。还指出了COVIDep的输出与COVID-19患者和临床前疫苗试验中记录的免疫反应之间的对应关系。该平台用户友好，灵活并且基于最新数据。它可能有助于指导SARS-CoV-2的疫苗设计和相关实验研究。