Children with perinatally acquired human immunodeficiency virus (PHIV) face a lifetime of combination antiretroviral treatment that often includes dolutegravir (DTG). DTG, an integrase strand inhibitor that has been linked to weight gain in adults, is increasingly being used in children. Understanding its potential short- and long-term sequelae in children is critically important. We report a case of excessive weight gain in a child with PHIV on DTG and provide a brief literature review.

中文翻译：

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围产期获得性人类免疫缺陷病毒 10 岁女性服用 Dolutegravir 导致体重过度增加：病例报告和文献回顾。

患有围产期获得性人类免疫缺陷病毒 (PHIV) 的儿童终生面临联合抗逆转录病毒治疗，其中通常包括多替拉韦 (DTG)。DTG 是一种整合酶链抑制剂，与成人体重增加有关，越来越多地用于儿童。了解其对儿童潜在的短期和长期后遗症至关重要。我们报告了一例 DTG 感染 PHIV 儿童体重增加过多的案例，并提供了简短的文献综述。