We report on 2 Asian siblings with X-linked inhibitor of apoptosis deficiency that arose from a novel deletion that presented with Epstein-Barr virus disease and hemophagocytic lymphohistiocytosis. This disease is ascribed to dysfunction in the nucleotide binding and oligomerization domain receptor pathway, tested using a modified muramyl dipeptide-mediated assay.

中文翻译：

---

一种新型 X 连锁细胞凋亡缺陷变体抑制剂，显示减毒的 Epstein-Barr 病毒反应。

我们报告了 2 个亚洲兄弟姐妹，他们患有 X 连锁细胞凋亡缺乏抑制剂，这些抑制剂是由一种新的缺失引起的，该缺失表现为 Epstein-Barr 病毒病和噬血细胞性淋巴组织细胞增生症。这种疾病归因于核苷酸结合和寡聚化结构域受体途径的功能障碍，使用改良的胞壁酰二肽介导的测定进行测试。