Purpose: The aim of the present retrospective single-center study is to evaluate the diagnostic performance of multiparametric ultrasonography for characterizing testicular tumors.

Method: Forty-nine patients with testicular tumors, 36 of malignant vs 13 of benign entity, were included in this retrospective single-center study on whom multiparametric sonography, encompassing native B-mode, Color Doppler, contrast-enhanced ultrasound (CEUS) and elastography, was performed between 2011–2018. In 48 of 49 patients, findings from multiparametric analysis were correlated with histopathological results. The applied contrast agent for CEUS was a second-generation blood pool agent. Ultrasonography examinations were performed and interpreted by a single experienced radiologist with more than 15 years of experience (EFSUMB Level 3).

Results: Multiparametric ultrasonography was successfully performed in all included patients without any adverse effects. Concomitant testicular microlithiasis, rapid arterial wash-in, elevated values for perfusion quantification – Peak Enhancement (PE), Wash-in Area Under the Curve (WiAUC) and Wash-in Perfusion Index (WiPI) – and higher shear wave velocities were significantly associated with malignancy.

Conclusions: Multiparametric ultrasonography depicts a non-ionizing, directly accessible and cost-effective imaging modality that allows for the extensive characterization of testicular tumors, thereby helping to discriminate between malignant and benign entity of testicular tumors.

目的：本回顾性单中心研究的目的是评估多参数超声检查对睾丸肿瘤的诊断性能。

方法：这项回顾性单中心研究纳入了49例睾丸肿瘤患者，其中恶性36例，良性13例，他们进行了多参数超声检查，包括自然B型，彩色多普勒，对比增强超声（CEUS）和弹性成像，在2011–2018年之间进行。在49位患者中的48位中，多参数分析的发现与组织病理学结果相关。用于CEUS的造影剂是第二代血池试剂。超声检查由一名经验丰富的放射科医生进行，并具有15年以上的经验（EFSUMB 3级）。

结果：所有纳入的患者均成功进行了多参数超声检查，没有任何不良反应。伴随的睾丸微石症症，快速动脉冲洗，灌注定量升高–峰增强（PE），曲线下冲洗面积（WiAUC）和冲洗灌注指数（WiPI）–较高的剪切波速度显着相关有恶性肿瘤。

结论：多参数超声检查描绘了一种非电离，可直接访问且具有成本效益的成像方式，可广泛表征睾丸肿瘤，从而有助于区分睾丸肿瘤的恶性和良性。