In the last decade, intervertebral disc (IVD) decellularization has gained significant attention for tissue regenerative purposes as a successful therapeutic alternative for low back pain (LBP). We discuss the recent advances in IVD decellularization, repopulation, and sterilization procedures, highlighting the major challenges that need to be addressed for clinical translation.

中文翻译：

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脱细胞支架，用于椎间盘再生。

在过去的十年中，椎间盘脱细胞（IVD）脱细胞获得了广泛的关注，用于组织再生，是一种成功的治疗腰痛（LBP）的替代方法。我们讨论了IVD去细胞，再填充和灭菌程序的最新进展，突出了临床翻译需要解决的主要挑战。