Abstract A new Ag+ and Sn2+ complexes of polymethyl methacrylate amide sulfadiazine (ligand H2L) were synthesized. The synthesized compounds were characterized by elemental analysis, TGA, SEM, TEM and spectral studies including 1H NMR, 13C NMR, FTIR, Electronic absorption and X-ray powder diffraction. The analytical and spectral technique used has identified that the H2L ligand acts as bidentate by amide group atoms of oxygen and nitrogen. For Ag+ and Sn2+ complexes the stoichiometry is 1:1 and 1:2 (M: Ligand) respectively. The results confirm the tetrahedral geometry of the Ag+ complex and an octahedral structure of the Sn2+ complex. The spectra of X-ray powder diffraction and TEM data show the nano-scale synthesized compounds. The antifungal activity of the synthesized ligand and its Ag+ and Sn2+ complexes was tested in vitro against the fungal Candida albicans before and after addition to the heat-polymerized acrylic denture base resin material. The data showed strong antifungal activity in the Sn2+ complex than in Ag+ complex and H2L ligand. Before and after combination with complexes H2L, Ag+, and Sn2+, the mechanical properties of acrylic denture base resin were studied. The results showed that the flexural strength, modulus, and hardness of acrylic denture base resin have improved than the control group. The addition of Sn2+ complex has decreased the deflection of acrylic resin more than H2L, while it has increased with the addition of Ag+ complex. Roughness decreased in heat-polymerized acrylic resin after adding H2L, Ag+, and Sn2+ complexes.

中文翻译：

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Ag+和Sn2+配合物的合成、表征及其在改善义齿基托材料生物学和力学性能方面的应用

摘要 合成了一种新型的聚甲基丙烯酸甲酯酰胺磺胺嘧啶（配体H2L）的Ag+和Sn2+配合物。合成的化合物通过元素分析、TGA、SEM、TEM 和光谱研究进行表征，包括 1H NMR、13C NMR、FTIR、电子吸收和 X 射线粉末衍射。使用的分析和光谱技术已经确定 H2L 配体作为氧和氮的酰胺基原子的双齿。对于 Ag+ 和 Sn2+ 复合物，化学计量比分别为 1:1 和 1:2（M：配体）。结果证实了 Ag+ 复合物的四面体几何形状和 Sn2+ 复合物的八面体结构。X 射线粉末衍射光谱和 TEM 数据显示了纳米级合成的化合物。在添加到热聚合的丙烯酸义齿基托树脂材料之前和之后，合成的配体及其 Ag+ 和 Sn2+ 配合物对真菌白色念珠菌的体外抗真菌活性进行了测试。数据显示 Sn2+ 复合物的抗真菌活性强于 Ag+ 复合物和 H2L 配体。在与配合物H2L、Ag+和Sn2+结合前后，研究了丙烯酸义齿基托树脂的力学性能。结果表明，丙烯酸义齿基托树脂的弯曲强度、模量和硬度均较对照组有所提高。Sn2+配合物的加入使丙烯酸树脂的挠度比H2L降低更多，而Ag+配合物的加入则增加了。添加 H2L、Ag+ 和 Sn2+ 配合物后，热聚合丙烯酸树脂的粗糙度降低。