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COVID-19 - Does This Disease Kill Due to Imbalance of the Renin Angiotensin System (RAS) Caused by Genetic and Gender Differences in the Response to Viral ACE 2 Attack?
Heart, Lung and Circulation ( IF 2.2 ) Pub Date : 2020-05-25 , DOI: 10.1016/j.hlc.2020.05.004
Ruth H Arnold 1
Affiliation  

Debate continues in the medical literature on the role of the renin angiotensin system (RAS) in Coronavirus disease 2019 (COVID-19) pathophysiology and the implications for the use of cardiovascular drugs acting on the RAS. Could these drugs – which include angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptors blockers (ARBs) – be harmful or potential key therapeutic agents in COVID-19? And, could potentially helpful measures be available and in plain view on the pharmacy shelf?



中文翻译:


COVID-19 - 这种疾病是否会因对病毒 ACE 2 攻击的反应中的遗传和性别差异导致肾素血管紧张素系统 (RAS) 失衡而导致死亡?



关于肾素血管紧张素系统 (RAS) 在 2019 年冠状病毒病 (COVID-19) 病理生理学中的作用以及使用作用于 RAS 的心血管药物的影响,医学文献中仍在继续争论。这些药物(包括血管紧张素转换酶抑制剂 (ACEIs) 和血管紧张素受体阻滞剂 (ARB))是否对 COVID-19 有害或可能是关键治疗药物?而且,是否可以在药房货架上找到并显而易见的潜在有用措施?

更新日期:2020-05-25
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