This present work deals with the synthesis of a series of organogel derived from substituted tyrosine derivatives via applying the concept of molecular engineering. Phenylalanine and tyrosine are structurally very similar amino acids. But only phenylalanine forms gels in both water and organic solvents. That is why the challenge was taken to transform tyrosine into a gelator and the concept of molecular engineering was applied. It was observed that a single nitro group is sufficient enough to transform it into a gelator. Not only a Boc-protected amino acid but also dipeptide and tripeptide were also found to produce organogel. Theoretical studies were also performed to understand the interactions involved during the gelation process. The gels derived from 1, 2, and 4 were found to be responsive towards a strong base like hydroxide which also helped us to get information regarding the gel model.

本工作涉及通过应用分子工程学概念，合成一系列衍生自取代酪氨酸衍生物的有机凝胶。苯丙氨酸和酪氨酸是结构上非常相似的氨基酸。但是只有苯丙氨酸在水和有机溶剂中都会形成凝胶。这就是为什么要挑战将酪氨酸转化为胶凝剂并应用分子工程的概念的原因。观察到单个硝基足以将其转化为胶凝剂。还发现不仅Boc保护的氨基酸，而且二肽和三肽也可产生有机凝胶。还进行了理论研究以了解胶凝过程中涉及的相互作用。衍生自凝胶1，2，和4 被发现对强碱如氢氧化物有反应，这也有助于我们获得有关凝胶模型的信息。