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Benzodiazepine misuse among adults receiving psychiatric treatment.
Journal of Psychiatric Research ( IF 3.7 ) Pub Date : 2020-05-24 , DOI: 10.1016/j.jpsychires.2020.05.020
R Kathryn McHugh 1 , Andrew D Peckham 1 , Thröstur Björgvinsson 1 , Francesca M Korte 2 , Courtney Beard 1
Affiliation  

Benzodiazepines are among the most commonly prescribed psychiatric medications and have the potential for misuse. People with psychiatric disorders may have a heightened liability to the reinforcing effects of benzodiazepines. Yet, the prevalence of benzodiazepine misuse in psychiatric care settings is not well characterized. The aim of the current study was to characterize the prevalence and correlates of benzodiazepine misuse in a sample of adults receiving psychiatric treatment (N = 589). The majority of participants reported a lifetime history of benzodiazepine prescription (68%) and 26% reported a lifetime history of misuse (defined as use without a prescription or at a dose or frequency higher than prescribed). Multivariable analyses indicated that history of a benzodiazepine prescription and drug use problems were significantly associated with lifetime benzodiazepine misuse. People with a history of benzodiazepine prescription had four times higher odds of misusing benzodiazepines and the primary source of misused benzodiazepines was from family or friends. Results suggest that benzodiazepine misuse is not exclusive to substance use disorder populations. The misuse of benzodiazepines should be assessed in psychiatric settings. Further research is needed to understand the impact of benzodiazepine misuse in this population and to develop tools to identify those at risk for misuse.



中文翻译:

接受精神病治疗的成年人滥用苯二氮卓类药物。

苯二氮卓类药物是最常用的精神科药物之一,有可能被滥用。患有精神疾病的人可能更倾向于苯二氮卓类药物的强化作用。然而,苯二氮卓类药物滥用在精神病护理环境中的普遍性尚未得到很好的表征。本研究的目的是在接受精神病治疗的成人样本(N = 589)中描述苯二氮卓类药物滥用的流行率和相关性。大多数参与者报告了苯二氮卓类药物的终生处方史 (68%),26% 报告了终生滥用的病史(定义为无处方使用或使用剂量或频率高于规定的剂量)。多变量分析表明,苯二氮卓类药物处方史和药物使用问题与终生苯二氮卓类药物滥用显着相关。有苯二氮卓类处方史的人滥用苯二氮卓类药物的几率要高出四倍,而滥用苯二氮卓类药物的主要来源是家人或朋友。结果表明,苯二氮卓类药物滥用不仅限于物质使用障碍人群。应在精神病学环境中评估苯二氮卓类药物的滥用情况。需要进一步研究以了解苯二氮卓类药物滥用对这一人群的影响,并开发工具来识别有滥用风险的人群。有苯二氮卓类处方史的人滥用苯二氮卓类药物的几率要高出四倍,而滥用苯二氮卓类药物的主要来源是家人或朋友。结果表明,苯二氮卓类药物滥用不仅限于物质使用障碍人群。应在精神病学环境中评估苯二氮卓类药物的滥用情况。需要进一步研究以了解苯二氮卓类药物滥用对这一人群的影响,并开发工具来识别有滥用风险的人群。有苯二氮卓类处方史的人滥用苯二氮卓类药物的几率要高出四倍,而滥用苯二氮卓类药物的主要来源是家人或朋友。结果表明,苯二氮卓类药物滥用不仅限于物质使用障碍人群。应在精神病学环境中评估苯二氮卓类药物的滥用情况。需要进一步研究以了解苯二氮卓类药物滥用对这一人群的影响,并开发工具来识别有滥用风险的人群。

更新日期:2020-05-24
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