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A rare case of gastric cancer with bilateral breast metastasis during pregnancy.
Journal of Oncology Pharmacy Practice ( IF 1.0 ) Pub Date : 2020-05-23 , DOI: 10.1177/1078155220925156
Tugba Basoglu 1 , Tugba Akin Telli 1 , Nazim Can Demircan 1 , Rukiye Arikan 1 , Ozlem Ercelep 1 , Salih Ozguven 2 , Sunullah Soysal 3 , Asli Memisoglu 4 , Faysal Dane 1 , Perran Fulden Yumuk 1
Affiliation  

BACKGROUND Gastric cancer is rare during pregnancy and often diagnosed at a later stage due to overlapping symptoms of pregnancy. Breast metastasis of gastric cancer is another uncommon entity. We present a rare case of breast metastasis of gastric cancer during pregnancy. CASE REPORT A 26-year-old female was diagnosed with gastric cancer at 14 weeks of gestation and underwent total gastrectomy. She rejected adjuvant chemotherapy and continued pregnancy without any follow-up. Cancer recurred in bilateral breasts at 34th week of gestation mimicking primary inflammatory breast cancer. MANAGEMENT AND OUTCOME It was difficult to diagnose breast metastasis during pregnancy because of overlapping pregnancy symptoms. Following an unresponsive period to antibiotherapy, a fine needle biopsy on breast was performed and signet cell adenocarcinoma metastasis was determined. We started chemotherapy after delivery. There was a near complete response after first line of chemotherapy. Unfortunately, cancer was relapsed within three months and we started second-line chemotherapy. DISCUSSION To our knowledge, this is the fourth case reported in medical literature of gastric cancer presented with breast metastasis during pregnancy. We will try to draw attention to diagnosis, treatment and different presentation of gastric cancer during pregnancy with review of the literature.

中文翻译:

妊娠期胃癌合并双侧乳腺转移的罕见病例。

背景技术胃癌在怀孕期间很少见,并且由于怀孕的重叠症状经常在后期被诊断出来。胃癌的乳房转移是另一个不常见的实体。我们提出了一个罕见的妊娠期胃癌乳腺转移病例。病例报告 一名 26 岁女性在妊娠 14 周时被诊断出患有胃癌,并接受了全胃切除术。她拒绝了辅助化疗并继续怀孕,没有任何随访。癌症在妊娠第 34 周时在双侧乳房复发,类似于原发性炎症性乳腺癌。管理和结果 由于妊娠症状重叠,妊娠期乳腺转移难以诊断。在对抗生素治疗无反应期后,对乳房进行了细针活检,并确定了印戒细胞腺癌的转移。我们在分娩后开始化疗。第一线化疗后几乎完全缓解。不幸的是,癌症在三个月内复发,我们开始了二线化疗。讨论 据我们所知,这是医学文献中报道的第四例胃癌在妊娠期间出现乳腺癌转移的病例。我们将通过文献回顾,试图引起人们对妊娠期胃癌的诊断、治疗和不同表现的关注。这是医学文献报道的第四例胃癌在妊娠期间出现乳腺癌转移的病例。我们将通过文献回顾,试图引起人们对妊娠期胃癌的诊断、治疗和不同表现的关注。这是医学文献报道的第四例胃癌在妊娠期间出现乳腺癌转移的病例。我们将通过文献回顾,试图引起人们对妊娠期胃癌的诊断、治疗和不同表现的关注。
更新日期:2020-05-23
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