Abstract Mining activities expose workers to diverse working conditions, rotational shifts and high altitude-related hypobaric hypoxia. Separately, each condition has been reported having a negative impact on miners’ health risk; however, the combination of both stressors has been poorly explored. The present study aimed to analyse the effects of exposure to rotational work shift (RWS) alone or in combination with high altitude-related chronic intermittent hypobaric hypoxia (CIHH) on cardiometabolic, physical activity and sleep quality related markers in copper miners from Los Pelambres mine in Chile. One hundred and eleven male miners working in RWS with or without CIHH were included. Anthropometrics measures, sleep quality assessment, physical activity level (PAL) and handgrip strength were evaluated. Exposure to CIHH exacerbated the detrimental effects of RWS as miners exposed to the combination of RWS and CIHH where more obese and had a wider neck circumference, reduced PAL at work and worsened sleep quality. Practitioner summary: The purpose was to assess cardiometabolic health and sleep quality markers associated with the combined effects of rotational shift work and high altitude-related intermittent hypobaric hypoxia in miners. Findings showed a wider neck circumference, lower physical activity level and higher prevalence of poor sleep quality in exposed miners. Abbreviations: ANOVA: analysis of variance; BM: body mass; BMI: body mass index; CI: confidence intervals; CIHH: chronic intermittent hypobaric hypoxia; CV: cardiovascular; CVR: cardiovascular risk; HA: high altitude; HACE: high-altitude cerebral edema; HGS: handgrip strength; IPAQ-SF: International Physical Activity Questionnaire - Short Form; LSD: Fisher's least standardized difference; MANCOVA: multivariate general lineal model; MET: metabolic equivalent; PAL: physical activity level; PSQI: Pittsburg sleep quality index; RWS: rotational work shift; WHR: waist-to-hip ratio

中文翻译：

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智利矿工轮换工作与高原相关慢性间歇性低压缺氧对心血管健康和睡眠质量的影响

摘要 采矿活动使工人面临不同的工作条件、轮班和高海拔相关的低压缺氧。另据报道，每种情况都会对矿工的健康风险产生负面影响；然而，对这两种压力因素的结合研究却很少。本研究旨在分析单独或与高海拔相关的慢性间歇性低气压缺氧 (CIHH) 接触轮换工作 (RWS) 对来自 Los Pelambres 矿的铜矿工的心脏代谢、身体活动和睡眠质量相关标志物的影响在智利。包括有或没有 CIHH 在 RWS 工作的 111 名男性矿工。评估了人体测量学测量、睡眠质量评估、身体活动水平 (PAL) 和握力。暴露于 CIHH 加剧了 RWS 的不利影响，因为矿工暴露于 RWS 和 CIHH 的组合中，更肥胖，颈围更宽，工作时 PAL 降低，睡眠质量恶化。从业者总结：目的是评估与轮班工作和与高海拔相关的间歇性低气压缺氧对矿工的综合影响相关的心脏代谢健康和睡眠质量标志物。结果表明，暴露在矿工中的矿工颈围更宽，体力活动水平更低，睡眠质量差的患病率更高。缩写：ANOVA：方差分析；BM：体重；BMI：体重指数；CI：置信区间；CIHH：慢性间歇性低压缺氧；CV：心血管；CVR：心血管风险；HA：高海拔；HACE：高原脑水肿；HGS：握力；IPAQ-SF：国际体育活动问卷 - 简表；LSD：Fisher 最小标准化差；MANCOVA：多元一般线性模型；MET：代谢当量；PAL：体力活动水平；PSQI：匹兹堡睡眠质量指数；RWS：轮班工作；WHR：腰臀比