Purpose

To compare the effects of high-load (≥ 70 of 1RM) and low-load (< 70 of 1RM) resistance training (RT) on femoral neck and lumbar spine bone mineral density (BMD) in middle-aged and older people.

Design

Systematic review with meta-analysis.

Data source

English language searches of the electronic databases PubMed/Medline, Scopus and Web of Science. Inclusion criteria: (i) older or middle-aged (≥ 45 years old) participants of both sexes with or without comorbidities, (ii) studies that compared high-load (≥70% 1 RM) versus low-load (<70% 1RM) RT, (iii) studies that examined femoral neck or lumbar spine BMD.

Results

From 1052 studies found, six were included in qualitative and quantitative analysis. The meta-analysis revealed no difference between groups for femoral neck (weighted mean difference [MD] and 95% confidence interval (CI) = 0.00 g/cm² [95% CI, −0.01 to 0.01]; P = 0.63) and lumbar spine (MD = 0.01 g/cm² [95% CI, −0.00 to 0.02]; P = 0.12) BDM. There was a substantial heterogeneity for femoral neck (I² = 47%; P = 0.07) and lumbar spine (I² = 59%; P = 0.02). Subgroup analysis revealed a significant effect of high-load RT on femoral neck BMD when participants presented normal BDM values (MD = 0.01 g/cm² [95% CI, −0.00 to 0.02]; P = 0.04) and on interventions lasting up to 6 months (MD = 0.01 g/cm² [95% CI, −0.00 to 0.02]; P = 0.03).

Conclusion

Both high- and low-load RT have similar effects on femoral neck and lumbar spine BMD in aging people.

中文翻译：

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高负荷和低负荷阻力训练对中老年人的骨矿物质密度产生相似的影响：对随机临床试验进行荟萃分析的系统评价。

目的

比较高负荷（≥1RM的70）和低负荷（<1RM的70）对中老年人股骨颈和腰椎骨矿物质密度（BMD）的影响。

设计

荟萃分析的系统评价。

数据源

电子数据库PubMed / Medline，Scopus和Web of Science的英语搜索。纳入标准：（i）有或无合并症的年龄较大或中年（≥45岁）参与者，（ii）比较高负荷（≥70％1 RM）与低负荷（<70％）的研究1RM）RT，（iii）检查股骨颈或腰椎骨密度的研究。

结果

从发现的1052项研究中，有6项被纳入定性和定量分析。荟萃分析显示两组之间的股骨颈（加权平均差异[MD]和95％置信区间（CI）= 0.00 g / cm ² [95％CI，-0.01至0.01]；P  = 0.63）没有差异脊柱（BMD）（MD = 0.01 g / cm ² [95％CI，-0.00至0.02]; P  = 0.12）。股骨颈（I ²  = 47％；P  = 0.07）和腰椎（I ²  = 59％；P  = 0.02）存在很大的异质性。亚组分析显示，当参与者呈现正常BDM值（MD = 0.01 g / cm）时，高负荷RT对股骨颈BMD有显着影响² [95％CI，-0.00至0.02]；P  = 0.04）和持续长达6个月的干预措施（MD = 0.01 g / cm ² [95％CI，-0.00至0.02]；P  = 0.03）。

结论

高负荷和低负荷RT对老年人的股骨颈和腰椎BMD具有相似的作用。