Biofuels and biochemicals derived from renewable resources are sconsidered as potential solutions for the energy crisis and associated environmental problems that human beings are facing today. However, so far the available types of bioderived chemicals are rather limited, and production efficiency is generally low. Expanding the realm of bioderived chemicals and relevant derivatives can help motivate the development of bioenergy and the general bioeconomy. Aldehydes, possessing unique reactivity, hold great promise as platform chemicals for producing a large portfolio of bioproducts. In this review, we focus on production of aldehydes from renewable bioresources and derivatization of aldehydes through chemocatalysis, biocatalysis, or de novo biosynthesis. Perspectives on combining protein engineering and cascade reactions for advanced aldehyde derivatization are also provided.

源自可再生资源的生物燃料和生物化学品被认为是解决当今人类面临的能源危机和相关环境问题的潜在解决方案。然而，目前可利用的生物衍生化学品种类相当有限，生产效率普遍较低。扩大生物衍生化学品及相关衍生物的领域，有助于推动生物能源和一般生物经济的发展。醛具有独特的反应性，作为生产大量生物产品组合的平台化学品具有很大的前景。在这篇综述中，我们专注于从可再生生物资源生产醛和通过化学催化、生物催化或从头衍生化醛生物合成。还提供了结合蛋白质工程和级联反应进行高级醛衍生化的观点。