Age-related metabolic and renal changes predispose older people to an increased risk of diabetes mellitus and diabetic kidney disease, respectively. As the prevalence of the ageing population is increasing, because of increased life expectancy, the prevalence of older people with diabetic kidney disease is likely to increase. Diabetic kidney disease is associated with an increased risk of adverse outcomes and increased costs to healthcare systems. The management includes promotion of a healthy lifestyle and control of cardiovascular risk factors such as hyperglycaemia, hypertension and dyslipidaemia. Older people are a heterogeneous group of people from a community-living fit and independent person to a fully dependent individual residing in a care home. Therefore, management in this age group should be based on a patient's functional level adopting tight metabolic control in the fit individual and relaxed targets in the frail person. However, despite the maximum available therapy, a significant number of patients with diabetic kidney disease still progress to renal failure and experience adverse cardiac outcomes. Therefore, future research is required to explore methods of early detection of diabetic kidney disease and to investigate novel therapeutic interventions to further improve the outcomes.Age-related metabolic and renal changes predispose older people to an increased risk of diabetes mellitus and diabetic kidney disease, respectively. As the prevalence of the ageing population is increasing, because of increased life expectancy, the prevalence of older people with diabetic kidney disease is likely to increase. Diabetic kidney disease is associated with an increased risk of adverse outcomes and increased costs to healthcare systems. The management includes promotion of a healthy lifestyle and control of cardiovascular risk factors such as hyperglycaemia, hypertension and dyslipidaemia. Older people are a heterogeneous group of people from a community-living fit and independent person to a fully dependent individual residing in a care home. Therefore, management in this age group should be based on a patient's functional level adopting tight metabolic control in the fit individual and relaxed targets in the frail person. However, despite the maximum available therapy, a significant number of patients with diabetic kidney disease still progress to renal failure and experience adverse cardiac outcomes. Therefore, future research is required to explore methods of early detection of diabetic kidney disease and to investigate novel therapeutic interventions to further improve the outcomes.Age-related metabolic and renal changes predispose older people to an increased risk of diabetes mellitus and diabetic kidney disease, respectively. As the prevalence of the ageing population is increasing, because of increased life expectancy, the prevalence of older people with diabetic kidney disease is likely to increase. Diabetic kidney disease is associated with an increased risk of adverse outcomes and increased costs to healthcare systems. The management includes promotion of a healthy lifestyle and control of cardiovascular risk factors such as hyperglycaemia, hypertension and dyslipidaemia. Older people are a heterogeneous group of people from a community-living fit and independent person to a fully dependent individual residing in a care home. Therefore, management in this age group should be based on a patient's functional level adopting tight metabolic control in the fit individual and relaxed targets in the frail person. However, despite the maximum available therapy, a significant number of patients with diabetic kidney disease still progress to renal failure and experience adverse cardiac outcomes. Therefore, future research is required to explore methods of early detection of diabetic kidney disease and to investigate novel therapeutic interventions to further improve the outcomes.

中文翻译：

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“社会”隔离措施和学校封锁对儿童和青少年心理健康的潜在影响。

年龄相关的代谢和肾脏变化分别使老年人患糖尿病和糖尿病性肾脏疾病的风险增加。随着人口老龄化的增加，由于预期寿命的延长，患有糖尿病肾病的老年人的患病率可能会增加。糖尿病肾病与不良后果的风险增加和医疗保健系统的成本增加相关。管理包括促进健康的生活方式和控制心血管危险因素，例如高血糖症，高血压和血脂异常。老年人是一群异族，从社区生活的适合和独立的人到居住在养老院中的完全依赖的个人。因此，该年​​龄段的管理应基于患者的 身体功能水平，对体弱的人要采取严格的新陈代谢控制措施，对体弱的人要放松目标。然而，尽管有最大的可用治疗方法，但仍有大量糖尿病肾病患者发展为肾功能衰竭，并经历不良的心脏预后。因此，需要进行进一步的研究以探索早期发现糖尿病性肾脏疾病的方法，并研究新的治疗性干预措施以进一步改善预后。与年龄有关的代谢和肾脏变化使老年人更易患糖尿病和糖尿病性肾脏疾病，分别。随着人口老龄化的增加，由于预期寿命的延长，患有糖尿病肾病的老年人的患病率可能会增加。糖尿病肾病与不良后果的风险增加和医疗保健系统的成本增加相关。管理包括促进健康的生活方式和控制心血管危险因素，例如高血糖症，高血压和血脂异常。老年人是一群异族，从社区生活的适合和独立的人到居住在养老院中的完全依赖的个人。因此，该年​​龄组的管理应基于患者的功能水平，对体弱者的身体进行严格的代谢控制，对体弱的人进行放松的控制。然而，尽管有最大的可用治疗方法，但仍有大量糖尿病肾病患者发展为肾功能衰竭，并经历不良的心脏预后。因此，与年龄有关的代谢和肾脏变化使老年人分别罹患糖尿病和糖尿病性肾脏疾病的风险增加，因此需要进行进一步的研究以探索早期发现糖尿病性肾脏疾病的方法，并研究新颖的治疗性干预措施以进一步改善预后。随着人口老龄化的增加，由于预期寿命的延长，患有糖尿病肾病的老年人的患病率可能会增加。糖尿病肾病与不良后果的风险增加和医疗保健系统的成本增加相关。管理包括促进健康的生活方式和控制心血管危险因素，例如高血糖症，高血压和血脂异常。老年人是一群异族，从社区生活的适合和独立的人到居住在养老院中的完全依赖的个人。因此，该年​​龄组的治疗应基于患者的功能水平，在体质健壮的个体中采用严格的代谢控制，在体弱的人群中采用宽松的目标。然而，尽管有最大的可用治疗方法，但仍有大量糖尿病肾病患者发展为肾功能衰竭，并经历不良的心脏预后。因此，需要进一步的研究来探索早期发现糖尿病性肾脏疾病的方法，并研究新的治疗性干预措施以进一步改善预后。该年龄组的管理应基于患者的功能水平，在健康的个体中采用严格的代谢控制，在体弱的患者中采用宽松的目标。然而，尽管有最大的可用治疗方法，但仍有大量糖尿病肾病患者发展为肾功能衰竭，并经历不良的心脏预后。因此，需要进一步的研究来探索早期发现糖尿病性肾脏疾病的方法，并研究新的治疗性干预措施以进一步改善预后。该年龄组的管理应基于患者的功能水平，在健康的个体中采用严格的代谢控制，在体弱的患者中采用宽松的目标。然而，尽管有最大的可用治疗方法，但仍有大量糖尿病肾病患者发展为肾功能衰竭，并经历不良的心脏预后。因此，需要进一步的研究来探索早期发现糖尿病性肾脏疾病的方法，并研究新的治疗性干预措施以进一步改善预后。