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In and Beyond COVID-19: US Academic Pharmaceutical Science and Engineering Community Must Engage to Meet Critical National Needs.
AAPS PharmSciTech ( IF 3.4 ) Pub Date : 2020-05-24 , DOI: 10.1208/s12249-020-01718-9
Vadim J Gurvich 1, 2 , Ajaz S Hussain 1, 3
Affiliation  

The supply of affordable, high-quality pharmaceuticals to US patients has been on a critical path for decades. In and beyond the COVID-19 pandemic, this critical path has become tortuous. To regain reliability, reshoring of the pharmaceutical supply chain to the USA is now a vital national security need. Reshoring the pharmaceutical supply with old know-how and outdated technologies that cause inherent unpredictability and adverse environmental impact will neither provide the security we seek nor will it be competitive and affordable. The challenge at hand is complex akin to redesigning systems, including corporate and public research and development, manufacturing, regulatory, and education ones. The US academic community must be engaged in progressing solutions needed to counter emergencies in the COVID-19 pandemic and in building new methods to reshore the pharmaceutical supply chain beyond the pandemic.

中文翻译:

超越COVID-19:美国学术药学和工程学界必须参与以满足关键的国家需求。

几十年来,向美国患者提供负担得起的高质量药物一直是至关重要的道路。在COVID-19大流行之外,这条关键道路已经变得曲折。为了恢复可靠性,将药品供应链转移到美国现在是国家安全的重要需求。用旧的专有技术和过时的技术来重新调配药品供应,这些技术会导致固有的不可预测性和不利的环境影响,既不会提供我们寻求的安全性,也不会具有竞争力和负担得起的价格。面临的挑战类似于重新设计系统,包括公司和公共研发,制造,法规和教育系统。
更新日期:2020-05-24
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