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ORGAN ABSORBED DOSE ESTIMATION REFLECTING SPECIFIC ORGAN MASSES WITH SIMPLE SCALING OF REFERENCE DOSES USING THE ORGAN MASSES.
Radiation Protection Dosimetry ( IF 0.8 ) Pub Date : 2020-05-22 , DOI: 10.1093/rpd/ncaa058
Kentaro Manabe 1, 2 , Shuji Koyama 3
Affiliation  

Estimating organ absorbed doses in consideration of person-specific parameters is important for radiation protection in diagnostic nuclear medicine. This study proposes a straightforward method for estimating the organ dose that reflects a specific organ mass by scaling the reference organ dose using the inverse ratio of the specific organ mass to the reference organ mass. For the administration of radiopharmaceuticals labelled by 99mTc or 123I, the organ doses for the liver, spleen, red marrow and thyroid obtained by the method were compared with those generated by a Monte Carlo simulation. The discrepancies were less than 14% for the liver, spleen and thyroid. Conversely, in some cases, the red marrow discrepancies were greater than 30% due to the wide distribution of red marrow in the trunk and head regions. This study confirms that the method of scaling organ doses can be effective for estimating mass-specific doses for solid organs.

中文翻译:

器官吸收剂量估计,反映了特定器官质量,并且使用器官质量对参考剂量进行了简单标定。

考虑个人特定参数估计器官吸收剂量对于诊断性核医学中的辐射防护很重要。这项研究提出了一种简单的方法,可以通过使用特定器官质量与参考器官质量的反比来缩放参考器官剂量,来估计反映特定器官质量的器官剂量。用于标有99m Tc或123的放射性药物I,将通过该方法获得的肝,脾,红骨髓和甲状腺的器官剂量与通过蒙特卡洛模拟产生的器官剂量进行比较。肝脏,脾脏和甲状腺的差异小于14%。相反,在某些情况下,由于红骨髓在躯干和头部区域的广泛分布,红骨髓差异大于30%。这项研究证实,缩放器官剂量的方法可以有效地估计实体器官的质量特异性剂量。
更新日期:2020-07-24
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