ABSTRACT The Mulberry plant (Morus spp.) is known for several phytochemicals. One such phytochemical is 1-deoxyjirinomycin (DNJ), which is based, on an iminosugar. The presence of DNJ has been reported in various parts of the mulberry plants section, such as leaves, latex, and root bark. DNJ is a well-known anti-diabetic agent due to its alpha-glucosidase inhibition activity. Apart from this, DNJ also exhibits anti-obesity, anti-microbial, anti-cancer, and cardioprotective properties. In this review, we have highlighted the presence of DNJ in different vegetative parts of mulberry, the pharmacological action of DNJ, and the mechanism of DNJ in regulating diabetes through a more comprehensive range of biochemical targets is also discussed.

中文翻译：

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桑椹 1-脱氧野尻霉素 (DNJ)：用于治疗的示例性化合物

摘要 桑属植物 (Morus spp.) 以多种植物化学物质而闻名。一种这样的植物化学物质是基于亚氨基糖的 1-脱氧吉林霉素 (DNJ)。据报道，DNJ 存在于桑树植物部分的各个部分，例如叶子、乳胶和根皮。由于其α-葡萄糖苷酶抑制活性，DNJ 是众所周知的抗糖尿病药。除此之外，DNJ 还具有抗肥胖、抗微生物、抗癌和保护心脏的特性。在这篇综述中，我们重点介绍了桑椹不同营养部位中 DNJ 的存在、DNJ 的药理作用以及 DNJ 通过更全面的生化靶点调节糖尿病的机制。