Natural Product Research ( IF 1.9 ) Pub Date : 2020-05-22 , DOI: 10.1080/14786419.2020.1768088 Chao Yuan 1 , Xue-Chun Shu 2 , Lin Fan 3 , Ying-Bo Zhang 1 , Ling-Liang Guan 1 , Fu-Lai Yu 1 , Xiao-Lu Chen 1 , Gang Li 4
Abstract
Three new paraconic acids, xylariacinics A–C (1–3), were isolated from the endophyte Xylariaceae sp. J4 harbored in the medicinal plant Blumea balsamifera. Their structures were elucidated on the basis of extensive spectroscopic data including HRMS, and NMR. The antibacterial efficacies of compounds 1–3 were evaluated against a panel of bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa. Their antifungal activities were also tested against Colletotrichum gloeosporioides. Unfortunately, all of them were inactive.
中文翻译:
来自内生真菌 Xylariaceae sp. 的新副康酸。J4
摘要
三种新的副康酸,木霉酸 A–C ( 1 – 3 ),是从内生菌木香科sp.中分离出来的。J4 存在于药用植物Blumea balsamifera 中。它们的结构是在广泛的光谱数据(包括 HRMS 和 NMR)的基础上阐明的。化合物的抗菌效力1 - 3对细菌如小组进行评价的金黄色葡萄球菌,枯草芽孢杆菌,大肠埃希氏菌和绿脓杆菌。它们的抗真菌活性也针对炭疽菌进行了测试. 不幸的是,他们都没有活动。