当前位置: X-MOL 学术Prenat. Diagn. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Pregnancy related pharmacokinetics and antimicrobial prophylaxis during fetal surgery, cefazolin and clindamycin as examples.
Prenatal Diagnosis ( IF 2.7 ) Pub Date : 2020-05-22 , DOI: 10.1002/pd.5753
Karel Allegaert 1, 2, 3 , Anouk E Muller 4, 5 , Francesca Russo 1, 6 , Sam Schoenmakers 7 , Jan Deprest 1, 6, 8 , Birgit C P Koch 3
Affiliation  

Antimicrobial prophylaxis during surgery aims to prevent post‐operative site infections. For fetal surgery, this includes the fetal and amniotic compartments. Both are deep compartments as drug equilibrium with maternal blood is achieved relatively late. Despite prophylaxis, chorio‐amnionitis or endometritis following ex utero intrapartum treatment or fetoscopy occur in 4.13% and 1.45% respectively of the interventions.

中文翻译:

胎儿手术期间与妊娠相关的药代动力学和抗菌药物预防,以头孢唑啉和克林霉素为例。

手术期间的抗生素预防旨在防止术后部位感染。对于胎儿手术,这包括胎儿和羊膜隔室。两者都是深隔室,因为与母体血液的药物平衡相对较晚。尽管采取了预防措施,但宫外产时治疗或胎儿镜检查后发生绒毛膜羊膜炎或子宫内膜炎的比例分别为 4.13% 和 1.45%。
更新日期:2020-05-22
down
wechat
bug