The differentiation of Alzheimer’s disease (AD) dementia from vascular dementia (VaD) and mixed‐type dementia (mixed dementia) requires stepwise analysis and usually occurs late in the disease process. Early diagnosis and therapy monitoring would benefit greatly from the identification of biomarkers of neurodegeneration, especially blood biomarkers. To this end, the aim of the present pilot study was to investigate differences in the distribution of peripheral T‐cell populations in patients with AD compared to VaD and mixed dementia.

中文翻译：

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阿尔茨海默氏病和血管性痴呆免疫表型的探索性研究。

阿尔茨海默氏病（AD）痴呆与血管性痴呆（VaD）和混合型痴呆（混合性痴呆）的区别需要逐步分析，通常发生在疾病过程的后期。鉴定神经退行性生物标志物，尤其是血液生物标志物，将对早期诊断和治疗监测有很大帮助。为此，本实验研究的目的是调查与VaD和混合性痴呆相比，AD患者外周T细胞分布的差异。