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Relationships between stroke, depression, generalized anxiety disorder and physical disability: some evidence from the Canadian Community Health Survey-Mental Health.
Psychiatry Research ( IF 4.2 ) Pub Date : 2020-05-22 , DOI: 10.1016/j.psychres.2020.113074
Xinyuan Li 1 , Xianquan Wang 2
Affiliation  

The objective of this study is to evaluate associations between stroke, depression, anxiety and physical disability. The sample of 19,159 participants aged ≥30 was obtained from the 2012 Canadian Community Health Survey–Mental Health. Depression or anxiety was defined as major depressive disorder (MDD) or generalized anxiety disorder (GAD) within the past 12 months. The history of anxiety was defined as GAD at any time point during the respondent's lifetime. Physical disability was assessed by the past 14-day disability in daily-living activities. For statistical analysis, two logistic regression models (crude and adjusted models) were presented. The results showed that subjects with stroke had greater likelihoods of MDD-GAD comorbidity and GAD only compared those without stroke. People with GAD only had higher likelihood of physical disability than those with neither of the two conditions. Among participants with stroke, lifetime GAD was associated with a greater likelihood of MDD. In conclusion, individuals with stroke may be vulnerable to comorbid depression-anxiety as well as anxiety only. Additionally, subjects with anxiety were more likely to have physical disability. The history of anxiety increased the risk for developing post-stroke depression.



中文翻译:

中风,抑郁,广泛性焦虑症和身体残疾之间的关系:加拿大社区健康调查-精神健康的一些证据。

这项研究的目的是评估中风,抑郁,焦虑和身体残疾之间的关联。来自2012年加拿大社区健康调查-精神健康的19,159名30岁以上的参与者的样本。抑郁或焦虑定义为过去12个月内的重度抑郁症(MDD)或广泛性焦虑症(GAD)。焦虑史定义为受访者一生中任何时间的GAD。通过在日常生活中过去14天的残疾来评估身体残疾。为了进行统计分析,提出了两个逻辑回归模型(粗模型和调整模型)。结果表明,患有中风的受试者发生MDD-GAD合并症的可能性更大,而仅患有GAD的受试者比没有中风的受试者高。与没有这两种情况的人相比,患有GAD的人身体残障的可能性更高。在患有中风的参与者中,终生GAD与MDD的可能性更大。总之,患有中风的人可能容易患合并抑郁症和焦虑症。另外,患有焦虑症的受试者更有可能患有身体残疾。焦虑史增加了中风后抑郁的风险。

更新日期:2020-05-22
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