SARS-CoV-2 (previously 2019-nCoV or Wuhan coronavirus) caused an unprecedented fast-spreading worldwide pandemic. Although currently with a rather low mortality rate, the virus spread rapidly over the world using the modern world’s traffic highways. The coronavirus (CoV) family members were responsible for several deadly outbreaks and epidemics during the last decade. Not only governments but also the scientific community reacted promptly to the outbreak, and information is shared quickly. For example, the genetic fingerprint was shared, and the 3D structure of key proteins was rapidly solved, which can be used for the discovery of potential treatments. An overview is given on the current knowledge of the spread, disease course, and molecular biology of SARS-CoV-2. We discuss potential treatment developments in the context of recent outbreaks, drug repurposing, and development timelines.

SARS-CoV-2（以前称为 2019-nCoV 或武汉冠状病毒）引起了前所未有的快速传播的全球大流行。尽管目前死亡率相当低，但该病毒利用现代世界的交通高速公路迅速传播到世界各地。在过去十年中，冠状病毒 (CoV) 家族成员造成了几次致命的爆发和流行病。不仅政府，科学界也对疫情迅速做出反应，信息共享迅速。例如，共享遗传指纹，快速解析关键蛋白质的 3D 结构，可用于发现潜在治疗方法。概述了当前有关 SARS-CoV-2 的传播、疾病过程和分子生物学的知识。我们在最近爆发的背景下讨论潜在的治疗进展，