Studies exploring the cognitive performance of bipolar patients have mainly been conducted in Western countries. To our knowledge, no surveys have been reported to date in Tunisia. The present work aimed to evaluate the cognitive functions, in the three domains of memory, attention and executive functions, among a sample of Tunisian individuals with bipolar disorder, during the remission period, compared to healthy control subjects. We found that Cognitive functions in euthymic patients with bipolar disorder were significantly more impaired than in controls, apart from the working memory that did not show a significant difference between the two groups. Our findings confirm cognitive deficits associated with bipolar disorder, even at a distance from the symptomatic phases of the disease. Thus, these anomalies may be considered as a trait marker of the disease. A better understanding of cognitive decline certainly allows for better management of psychiatric pathologies, thus improving patients’ social skills and quality of life.

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突尼斯双相情感障碍患者的认知障碍：病例对照研究

探索双相情感障碍患者认知表现的研究主要在西方国家进行。据我们所知，迄今为止在突尼斯尚未报告任何调查。目前的工作旨在评估与健康对照受试者相比，在缓解期突尼斯双相情感障碍患者样本中记忆、注意力和执行功能三个领域的认知功能。我们发现，除了工作记忆在两组之间没有显着差异外，双相情感障碍正常患者的认知功能受损程度明显高于对照组。我们的研究结果证实了与双相情感障碍相关的认知缺陷，即使与疾病的症状阶段相距甚远。因此，这些异常可能被认为是疾病的特征标志。更好地了解认知衰退当然可以更好地管理精神疾病，从而提高患者的社交技能和生活质量。