Purpose of Review

Idiopathic intracranial hypertension (IIH) is a disorder characterized by long-standing elevated intracranial pressure (ICP). As the name applies, no uniform cause has been identified. IIH is typically characterized by headaches, pulsatile tinnitus, and visual deterioration.

Recent Findings

Anomalies in cerebrospinal fluid (CSF) absorption are implicated in the pathophysiology of IIH. Non-invasive imaging of the brain parenchyma and the cerebral venous sinus has improved, and research has gained a better understanding of the role of cerebral venous sinus stenosis. Both have led to a better delineation of the role of arachnoid granulations (AG) and the glymphatic system in the development of IIH.

Summary

IIH may occur as a result of restrictions of CSF absorption from the venous system, and or the congestion and overflow of the glymphatic system. Elucidating these mechanisms will lead to greater understanding of its underlying pathophysiologic mechanisms.

中文翻译：

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蛛网膜颗粒和淋巴系统在特发性颅内高压病理生理学中的作用。

审查目的

特发性颅内高压 (IIH) 是一种以长期颅内压 (ICP) 升高为特征的疾病。顾名思义，尚未确定统一的原因。IIH 的典型特征是头痛、搏动性耳鸣和视力下降。

最近的发现

脑脊液 (CSF) 吸收异常与 IIH 的病理生理学有关。脑实质和脑静脉窦的无创成像有所改善，研究对脑静脉窦狭窄的作用有了更好的认识。两者都有助于更好地描述蛛网膜颗粒 (AG) 和淋巴系统在 IIH 发展中的作用。

概括

IIH 可能是由于静脉系统对 CSF 吸收的限制，或淋巴系统充血和溢出所致。阐明这些机制将有助于更好地了解其潜在的病理生理机制。