As the demand for phenolic compounds in pharmaceutical, food, nutraceutical, and cosmetic production is escalating, recovery of phenolic compounds from bioresources has been receiving great concerns from the scientific community. Renewable, environmentally benign, and biocompatible choline chloride–based deep eutectic solvents (Ch-DESs) are considered potential alternatives to conventional solvents in phenolic compound extraction. In the past 2 years, numerous innovative studies centered on phenolic compound extraction using Ch-DESs and process variable optimization have been explored. Thus, this review aims to summarize the updated state-of-the-art effort dedicated to phenolic compounds extraction from various bioresources using Ch-DESs. Furthermore, impact factors, kinetic modeling, and chemical mechanisms of the process are thoroughly analyzed and discussed. Finally, prospects and challenges in commercialization of phenolic compound extraction from bioresources using Ch-DESs are indicated and extensively discussed.

随着制药，食品，营养保健品和化妆品生产中对酚类化合物的需求不断增加，从生物资源中回收酚类化合物一直受到科学界的关注。可再生，对环境无害且具有生物相容性的基于氯化胆碱的深共熔溶剂（Ch-DES）被认为是酚类化合物萃取中常规溶剂的潜在替代品。在过去的两年中，已经进行了许多有关使用Ch-DES提取酚类化合物和优化工艺变量的创新研究。因此，本综述旨在总结致力于使用Ch-DES从各种生物资源中提取酚类化合物的最新技术成果。此外，影响因素，动力学建模，并对过程的化学机理进行了彻底的分析和讨论。最后，指出并广泛讨论了使用Ch-DES从生物资源中提取酚类化合物的商业化前景和挑战。