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Mitochondrial translation, dynamics, and lysosomes combine to extend lifespan
Journal of Cell Biology ( IF 7.4 ) Pub Date : 2020-05-20 , DOI: 10.1083/jcb.202005084
Levi Ali 1 , Cole M Haynes 1
Affiliation  

In this issue, Liu et al. (2019. J. Cell. Biol.https://doi.org/10.1083/jcb.201907067) find that the inhibition of mitochondrial ribosomes in combination with impaired mitochondrial fission or fusion increases C. elegans lifespan by activating the transcription factor HLH-30, which promotes lysosomal biogenesis.

中文翻译:

线粒体翻译、动力学和溶酶体相结合可延长寿命

在本期中,刘等人。(2019. J. Cell. Biol.https://doi.org/10.1083/jcb.201907067) 发现,线粒体核糖体的抑制与线粒体裂变或融合受损相结合,可以通过激活转录因子 HLH- 来延长线虫的寿命。 30,促进溶酶体生物发生。
更新日期:2020-05-20
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