Background: Burn injury continues to be a significant cause of morbidity and death, with infectious complications being the primary cause of death. Patients are susceptible to overwhelming infection secondary to both the physical breakdown of the skin and mucosal barrier and the immune dysfunction that accompanies the inflammatory response to a major burn. With resistance to traditional antibiosis looming as a serious threat to patient outcome, advancement in the treatment of burn infections is imperative.

中文翻译：

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治疗烧伤感染的新疗法

背景：烧伤仍然是发病和死亡的一个重要原因，感染性并发症是主要的死亡原因。继发于皮肤和粘膜屏障的物理破坏以及伴随着对严重烧伤的炎症反应的免疫功能障碍，患者容易受到严重感染。由于对传统抗生素的耐药性正在成为对患者预后的严重威胁，因此必须推进烧伤感染的治疗。