Objective . This paper describes the design, testing and use of a novel multichannel block-capable stimulator for acute neurophysiology experiments to study highly selective neural interfacing techniques. This paper demonstrates the stimulator’s ability to excite and inhibit nerve activity in the rat sciatic nerve model concurrently using monophasic and biphasic nerve stimulation as well as high-frequency alternating current (HFAC). Approach . The proposed stimulator uses a Howland Current Pump circuit as the main analogue stimulator element. 4 current output channels with a common return path were implemented on printed circuit board using Commercial Off-The-Shelf components. Programmable operation is carried out by an ARM Cortex-M4 Microcontroller on the Freescale freedom development platform (K64F). Main results . This stimulator design achieves ± 10 mA of output current with ± 15 V of compliance and less than 6 µ A of resolution using a quad-channel ...

中文翻译：

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用于急性神经生理学的 HFAC 模块和模块可扩展 4 通道刺激器。

客观的 。本文描述了用于急性神经生理学实验的新型多通道阻塞刺激器的设计、测试和使用，以研究高选择性的神经接口技术。本文展示了刺激器同时使用单相和双相神经刺激以及高频交流电 (HFAC) 在大鼠坐骨神经模型中激发和抑制神经活动的能力。方法 。建议的刺激器使用 Howland Current Pump 电路作为主要的模拟刺激器元件。使用商用现货组件在印刷电路板上实现了 4 个具有公共返回路径的电流输出通道。可编程操作由飞思卡尔自由开发平台 (K64F) 上的 ARM Cortex-M4 微控制器执行。主要结果。