Abstract

Background: Cardiac damage is frequently referred to in patients with SARS-CoV-2, is usually diagnosed by enzyme elevations, and is generally thought to be due to underlying coronary artery disease. There are references to cardiomyopathies accompanying coronavirus, but there has been no histologic confirmation.

Case report: A previously healthy 17 year male old presented in full cardiac arrest to the emergency department after a 2 day history of headache, dizziness, nausea and vomiting. Autopsy demonstrated an enlarged flabby heart with eosinophilic myocarditis. There was no interstitial pneumonia or diffuse alveolar damage. Postmortem nasopharyngeal swabs detected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) known to cause coronavirus disease 2019 (COVID-19). No other cause for the eosinophilic myocarditis was elucidated.

Conclusion: Like other viruses, SARS-CoV-2 may be associated with fulminant myocarditis.

摘要

背景：心脏损害在SARS-CoV-2患者中经常提及，通常通过酶升高来诊断，通常被认为是由于潜在的冠状动脉疾病所致。有冠状病毒伴发的心肌病的参考文献，但尚无组织学证实。

病例报告：一名先前健康的17岁男性，在头痛，头晕，恶心和呕吐两天后，就被送往急诊室进行了全心脏骤停。尸检显示心脏松弛，并伴有嗜酸性心肌炎。无间质性肺炎或弥漫性肺泡损害。死后鼻咽拭子检测到严重急性呼吸系统综合症冠状病毒2（SARS-CoV-2），已知会导致冠状病毒病2019（COVID-19）。没有其他原因引起的嗜酸性心肌炎被阐明。

结论：与其他病毒一样，SARS-CoV-2可能与暴发性心肌炎有关。