OBJECTIVE Substantial research has accrued in support of a key role for social processes in substance use disorders (SUD). Researchers have developed a range of interventions that capitalize on these social processes to bolster treatment outcomes by involving significant others (e.g., romantic partners, family, friends) in SUD treatment. Yet dissemination of these treatments to many contexts has been slow, and information on their broad efficacy is lacking. This meta-analysis aims to quantify the effect of significant other involvement in SUD treatments above and beyond individually-based therapies. METHOD A total of 4,901 records were screened for randomized controlled trials examining the effect of Significant Other Involved SUD Treatments (SOIT) versus individually-based active comparator treatments. Our search yielded 77 effect sizes based on data from 2,115 individuals enrolled in 16 independent trials. RESULTS Findings indicated a significant effect of SOIT above and beyond individually-based active comparator treatments for reducing substance use and substance-related problems, d = 0.242, 95% CI [0.148, 0.336], I² = 10.596, Q(15) = 16.778. This effect was consistent across SOIT treatment types and endured 12-18 months after the end of treatment. Analyses of raw mean differences indicated that this effect translates to a 5.7% reduction in substance use frequency-the equivalent of approximately 3 fewer weeks a year of drinking/drug use. CONCLUSION Findings indicate a significant advantage for SOIT in SUD treatment, and hold interesting conceptual implications for theories of SUD maintenance. (PsycINFO Database Record (c) 2020 APA, all rights reserved).

中文翻译：

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其他重大参与药物滥用疾病治疗的影响：荟萃分析。

目的大量研究支持了物质滥用障碍（SUD）中社会过程的关键作用。研究人员已经开发出一系列干预措施，这些干预措施可利用这些社会过程，通过让其他重要人员（例如，浪漫伴侣，家人，朋友）参与SUD治疗来增强治疗效果。然而，将这些疗法传播到许多场合的进展缓慢，并且缺乏有关其广泛疗效的信息。这项荟萃分析旨在量化除基于个体的疗法之外，SUD治疗中其他重要参与的影响。方法总共筛选了4,901条记录，以进行随机对照试验，以检验其他重大SUD治疗（SOIT）与基于个体的主动比较剂治疗的疗效。根据来自16个独立试验的2115名受试者的数据，我们的搜索产生了77种效应量。结果发现表明，SOIT优于单独使用基于活性的比较剂治疗，可减少物质使用和与物质有关的问题，d = 0.242，95％CI [0.148，0.336]，I²= 10.596，Q（15）= 16.778 。该效果在各种SOIT治疗类型中均一致，并在治疗结束后持续12-18个月。对原始均值差异的分析表明，这种影响意味着物质使用频率降低了5.7％，相当于每年减少饮酒/吸毒3周。结论研究结果表明SOIT在SUD治疗中具有显着优势，并且对SUD维护理论具有有趣的概念意义。（PsycINFO数据库记录（c）2020 APA，