The 2019 novel coronavirus (nCoV) pandemic is rapidly developing across the globe and new information is emerging expeditiously and constantly, particularly in relation to neurological illnesses. Both central and peripheral nervous system involvement has been reported including headache, dizziness, hyposmia/anosmia, taste disturbances, seizures, stroke, alteration of the sensorium, and even acute hemorrhagic necrotizing leukoencephalopathy. Varying degrees of olfactory disturbances may pre-empt the diagnosis of COVID-19. Although no direct effect of 2019 nCoV has been reported yet on Parkinson's disease, there are enormous possible indirect effects and implications. We examine the potential effects and challenges posed by this pandemic to individuals with Parkinson's disease, particularly in the Indian context where telecommunication access or support group access may be lacking for these patients. Additionally, lockdown and social distancing may pose hurdles in the provision of optimum medical therapy, particularly if patients experience motor and non-motor deteriorations due to diverse reasons.


中文翻译：

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COVID-19 大流行期间管理帕金森病患者的挑战。


2019 年新型冠状病毒 (nCoV) 大流行正在全球范围内迅速发展，新信息不断迅速涌现，特别是与神经系统疾病相关的信息。据报道，中枢和周围神经系统均受累，包括头痛、头晕、嗅觉减退/嗅觉丧失、味觉障碍、癫痫发作、中风、感觉中枢改变，甚至急性出血坏死性白质脑病。不同程度的嗅觉障碍可能会抢先诊断出 COVID-19。尽管尚未报道 2019 新型冠状病毒对帕金森病的直接影响，但可能存在巨大的间接影响和影响。我们研究了这种流行病对帕金森病患者带来的潜在影响和挑战，特别是在印度，这些患者可能缺乏电信接入或支持团体接入。此外，封锁和社交距离可能会对提供最佳的医疗治疗造成障碍，特别是如果患者由于各种原因出现运动和非运动恶化。