This study aimed to provide a model of awareness in Alzheimer’s disease using the stage of the disease as a risk factor. Awareness was assessed using three methods (patient-caregiver discrepancy, prediction-performance discrepancy, clinical rating). Twenty-five healthy control subjects and sixty-one patients participated, with measures of cognition, apathy, depression, and awareness. These measures were introduced into a manual backward regression. Confounding factors impacting at least 15% of the exposure factor estimate were maintained in the model. Except for the prediction performance discrepancy, also presenting cognitive associations, the other awareness assessments suggested a major role of depression and apathy as impacting factors.

中文翻译：

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在阿尔茨海默氏病中建立意识模型。

这项研究旨在通过将疾病的阶段作为危险因素，提供对阿尔茨海默氏病认识的模型。使用三种方法（患者-护理人员差异，预测表现差异，临床评分）评估意识。25名健康对照受试者和61名患者参加了这项活动，测量了认知，冷漠，抑郁和意识水平。这些度量已引入到手动向后回归中。在模型中保留了影响至少15％暴露因子估计的混杂因子。除了预测表现差异外，还表现出认知联系，其他意识评估表明抑郁和冷漠是影响因素的主要作用。