Background/Aims: It is important to appropriately manage patients with procedure-related artificial mucosal ulcers or procedure-related complications. Many endoscopic closure techniques have been reported; however, they often require the use of special devices. We developed a single-channel endoscopic closure technique (SCCT) that can be performed with conventional devices. In the present study, we describe the technique and evaluate its efficacy. Methods: Twenty-five consecutive patients who underwent endoscopic treatment and whose artificial ulcer was closed using the SCCT were enrolled in this study. The technical success rate, number of clips for closure, procedure time, complication rate on the day of the procedure, clinical success rates on days 1 and 5, and incidence of severe stenosis of the gastrointestinal (GI) tract at 2 months after the procedure were evaluated. Results: The median ulcer diameter was 20 mm. The tumor locations were the stomach (n = 19), jejunum (n = 1), and colon (n = 5). The technical success rate was 100% (25/25), and the rate of incomplete closure was 0% (0/25). Eight clips were needed on average. The median procedure time was 18 min (range 5–49 min). The complication rate was 0% (25/25). The clinical success rates on days 1 and 5 were 100% (19/19) and 100% (9/9), respectively. No patients presented stenosis as a late complication at 2 months after the procedure (0/25). Conclusion: The SCCT could be applied in the treatment of artificial ulcers in several parts of the GI tract with a high clinical success rate and no complications. The SCCT appears to be a good option for closing artificial mucosal ulcers.
Gastrointest Tumors 2020;7:21–29

中文翻译：

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内窥镜治疗相关人工溃疡的有前途的单通道内窥镜闭合技术的疗效和安全性：一项初步研究。

背景/目的：对患有手术相关人工黏膜溃疡或手术相关并发症的患者进行适当管理非常重要。已经报道了许多内窥镜闭合技术；但是，它们通常需要使用特殊设备。我们开发了一种单通道内窥镜闭合技术 (SCCT)，可以使用传统设备进行。在本研究中，我们描述了该技术并评估其功效。方法：本研究招募了 25 名连续接受内镜治疗并使用 SCCT 闭合人工溃疡的患者。技术成功率、闭合夹数、手术时间、手术当天并发症发生率、第1天和第5天临床成功率、术后2个月胃肠道（GI）严重狭窄发生率进行了评估。结果：中位溃疡直径为 20 mm。肿瘤位置是胃（n = 19）、空肠（n = 1）和结肠（n= 5)。技术成功率为100%（25/25），不完全闭合率为0%（0/25）。平均需要八个剪辑。中位手术时间为 18 分钟（范围 5-49 分钟）。并发症发生率为 0% (25/25)。第 1 天和第 5 天的临床成功率分别为 100% (19/19) 和 100% (9/9)。没有患者在术后 2 个月出现狭窄作为晚期并发症 (0/25)。结论： SCCT可应用于消化道多部位人工溃疡的治疗，临床成功率高，无并发症发生。SCCT 似乎是闭合人工黏膜溃疡的好选择。
胃肠肿瘤 2020；7:21–29