Caffeine is the most commonly ingested psychoactive substance in the world. Although caffeine-use disorder is not recognized as a formal diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, five disorders related to caffeine use are enumerated therein. An evolving literature suggests that caffeine is one of many licit substances that may cause psychotic symptoms in higher doses. Here, we present a case in which a defendant ingested large quantities of caffeine, which result in transient psychosis and a successful affirmative defense of involuntary intoxication. The purpose of this article is to summarize states' statutory approaches to involuntary intoxication, given that the term is defined variably, if defined at all. Evaluators must be careful to apply jurisdictionally appropriate standards in involuntary intoxication defenses because the bar for this total defense differs across localities.

中文翻译：

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咖啡因诱发的精神病和非自愿中毒的法定方法的回顾。

咖啡因是世界上最普遍摄入的精神活性物质。尽管在《精神障碍诊断和统计手册》第五版中并未将咖啡因使用障碍识别为正式诊断，但其中列举了五种与咖啡因使用有关的障碍。不断发展的文献表明，咖啡因是许多合法物质中的一种，高剂量可能会导致精神病性症状。在这里，我们介绍了一个案例，在该案例中，被告摄入了大量咖啡因，导致短暂性精神病和对非自愿中毒的成功肯定防御。本文的目的是总结州对非自愿性中毒的法定方法，因为该术语的定义是可变的（如果有定义的话）。