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Synthesis and properties of porous piezoelectric BT/PHBV composite scaffold.
Journal of Biomaterials Science, Polymer Edition ( IF 3.6 ) Pub Date : 2020-05-13 , DOI: 10.1080/09205063.2020.1764164
Hua Jiao 1 , Sen Song 1 , Kang Zhao 1 , Xinyuan Zhang 1 , Yufei Tang 1
Affiliation  

The biodegradable material poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) scaffold has good biodegradability, but poor biocompatibility limits its application in the biological field. And it can effectively improve its biological activity by compounding with the bone conduction activity material of Barium titanate (BT). The PHBV and piezoelectric material BT were prepared into porous composite scaffolds with porosity of 45–50%. The mechanical properties and electrical properties of BT/PHBV scaffolds were systematically studied. The results showed that the piezoelectric coefficient d33 was 0.2–1.5 pC/N. Moreover, the compressive strength and elastic modulus were 1.0–2.0 MPa and 100–200 MPa, respectively. The results of degradation and mineralization showed that BT/PHBV scaffolds had good degradation and mineralization performance which was indicated that the materials had good biological activity.



中文翻译:

多孔压电BT/PHBV复合支架的合成与性能[J].

可生物降解材料聚(3-羟基丁酸酯-co-3-羟基戊酸酯)(PHBV)支架具有良好的生物降解性,但较差的生物相容性限制了其在生物领域的应用。并与钛酸钡(BT)骨传导活性物质复合,可有效提高其生物活性。将 PHBV 和压电材料 BT 制备成孔隙率为 45-50% 的多孔复合支架。系统研究了BT/PHBV支架的机械性能和电性能。结果表明,压电系数d 33为 0.2–1.5 pC/N。此外,压缩强度和弹性模量分别为 1.0-2.0 MPa 和 100-200 MPa。降解矿化结果表明BT/PHBV支架具有良好的降解矿化性能,表明该材料具有良好的生物活性。

更新日期:2020-05-13
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